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Growth hormone is responsible for the increase in height as children grow, but scientists have shown that it has generalized effects on protein, lipid, and carbohydrate metabolism
We want to ensure scientists have access to reliable materials that support reproducible research results
Infants with PWS also show other clinical signs of GHD, such as low muscle tone, small hands and feet, increased body fat percentage, and reduced lean mass
This is particularly significant for patients with type 2 diabetes, who are already at an increased risk of these conditions
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Preclinical work has reported a distinct selectivity profile, with growth hormone stimulation observed at concentrations that did not trigger ACTH or cortisol secretion, making it a useful tool for isolating growth hormone-specific signalling without activation of the hypothalamic-pituitary-adrenal axis
